Chapter 6: CRISPR
Clustered Regularly Interspaced Short Palindromic Repeats
Class Notes and Handouts
Bozeman Science - Overview of CRISPR (YouTube, 7:20 min.)
PowerPoint Presentations
Coming soon.
Activities
Click & Learn - CRISPR-Cas 9 Mechanism and Applications (HHMI)
Laboratory Investigations
Lab 1: 'Out of the Blue' CRISPR Experiment
Part 1: Introduction to CRISPR-Cas9 Gene Editing Technology (pdf)
Part 2: lacZ CRISPR Gene Editing Laboratory (pdf)
Lab Procedures for Part 2 (pdf)
Part 3 : Identification and Bioinformatics Analysis of Cas9 Target Sites (pdf)
Lab 2: Out of the Blue CRISPR - Genotyping Extension
Information coming soon.
Videos & Animations
How CRISPR lets us edit our DNA (TED video, 15:33 min. September, 2015)
What you need to know about CRISPR (TED video, 9:53 min. June, 2016)
Genome Editing with CRISPR-Cas9 (YouTube, 4:12 min.)
Study Guides
Coming soon.
Media Articles
Rewriting the Code if Life (New Yorker, Jan. 2017)
DNA- editing breakthrough could fix 'broken genes' in the brain, delay aging and cure incurable diseases (The Independent, Nov. 2016)
The Gene Genie (Scientific American, DEc. 2014)
The Battle of CRISPR (FiveThirtyEight, Jan, 2016)
Ethical Considerations - Rogue Gene Editing of Human Embryos (New York Times, Jan. 2019)
Bozeman Science - Overview of CRISPR (YouTube, 7:20 min.)
PowerPoint Presentations
Coming soon.
Activities
Click & Learn - CRISPR-Cas 9 Mechanism and Applications (HHMI)
Laboratory Investigations
Lab 1: 'Out of the Blue' CRISPR Experiment
Part 1: Introduction to CRISPR-Cas9 Gene Editing Technology (pdf)
Part 2: lacZ CRISPR Gene Editing Laboratory (pdf)
Lab Procedures for Part 2 (pdf)
Part 3 : Identification and Bioinformatics Analysis of Cas9 Target Sites (pdf)
Lab 2: Out of the Blue CRISPR - Genotyping Extension
Information coming soon.
Videos & Animations
How CRISPR lets us edit our DNA (TED video, 15:33 min. September, 2015)
What you need to know about CRISPR (TED video, 9:53 min. June, 2016)
Genome Editing with CRISPR-Cas9 (YouTube, 4:12 min.)
Study Guides
Coming soon.
Media Articles
Rewriting the Code if Life (New Yorker, Jan. 2017)
DNA- editing breakthrough could fix 'broken genes' in the brain, delay aging and cure incurable diseases (The Independent, Nov. 2016)
The Gene Genie (Scientific American, DEc. 2014)
The Battle of CRISPR (FiveThirtyEight, Jan, 2016)
Ethical Considerations - Rogue Gene Editing of Human Embryos (New York Times, Jan. 2019)
Podcasts
'Evolution Accelerated' (Freakonomics, 40 min.)
'Evolution Accelerated' (Freakonomics, 40 min.)