Chapter 4: DNA Structure and Analysis (J. Kirk Brown Text)
Ch. 4 Introduction to Studying DNA (Ellyn Daugherty Text)
Class Notes and Handouts
Ch.4 Class Notes (pdf)
Chapter Objectives and Essential Vocabulary (Google Doc)
Chapter 4 Key Terms (pdf)
Forensic DNA Fingerprinting (pdf)
Molecules of Inheritance (website)
DNA Replication (Bozeman Science, 10:09 min.)
PowerPoint Presentations
Chapter 4 Background Information
DNA Structure & Function (pptx)
Sources of DNA (pptx)
RFLP & DNA Fingerprinting (pptx)
Recombinant DNA and Applications (pptx)
Sickle Cell & Gel Electrophoresis - how we use this technique to ID a person's genotype (pptx)
Activities
DNA Extraction Activity (pdf)
DNA Extraction - Why Use Detergent? (pdf)
Advanced Paper DNA Model (pdf)
Shorter, simplified directions for Paper DNA Model (pdf)
' Biotech Stocks are Hot' Stock Market Activity (pdf)
DNA Fingerprinting Scenarios (pdf)
Casting Agarose Gels Protocol - refer to p. 117 of the J. Kirk Brown textbook.
Laboratory Investigations
Lab 1: Restriction Site Prediction Using NEBcutter Protocol - refer to p. 75 of the J. Kirk Brown textbook.
Lab 2: Casting Agarose Gels Protocol - refer to p. 117 of the J. Kirk Brown textbook.
Lab 3: Dye Electrophoresis - refer to p. 119 of the J. Kirk Brown textbook.
Lab 4: Bio-Rad Restriction Digestion and Analysis of Lambda DNA - refer to p. 121 of the J. Kirk Brown textbook. For additional notes for this lab click this link: Lambda DNA Notes. For more detailed lab procedures click this link: Bio-Rad Restriction Digestion and Analysis of Lambda DNA.
Lab 5: Forensic DNA Fingerprinting - refer to p. 126 of the J. Kirk Brown textbook.
Lab 6: Plasmid Mapping - refer to p. 131 of the J. Kirk Brown textbook.
Virtual Laboratory Experiments
Gel Electrophoresis
Gel Electrophoresis Virtual Lab (University of Utah)
CSI Wildlife & DNA Profiling using STRs
Part 1: CSI Wildlife: Analyzing Genetic Evidence - Handout 1 (pdf)
Part 2: CSI Wildlife: Using Genetics to Hunt Elephant Poachers - Handout 2 (pdf)
Part 3: CSI Wildlife: Frequency Primer - Handout 3 (pdf)
Part 4: DNA Profiling using STRs (pdf)
Bioethics
Limited Medications. Who Gets It? (pdf, Daugherty textbook)
Videos & Animations
DNA Replication
DNA Replication (Bozeman Science, 10:09 min.)
DNA Replication animation (YouTube, 3:37 min.)
DNA Gel Electrophoresis 3D Animation (YouTube, 0:32 min.)
Transcription & Translation
Transcription animation This is an excellent animation of the process of TRANSCRIPTION.
Translation animation This is an excellent animation of the process of TRANSLATION.
DNA & RNA
HHMI Video Animations - DNA & RNA
The Art of DNA Folding. This animated video shows how and why DNA folds (YouTube, 8:27 Min.)
Central Dogma of Biology, 3D Animation (DNALC, 2:51 Min.)
How DNA is Packaged, 3D Animation (DNALC, 1:30 Min.)
Interesting Webpages
DNA through Nobel Prize.org Learn about genetics and DNA through this interactive site.
DNA to Protein From DNA to protein - a comprehensive site from The University of Utah.
DNA from the Beginning - an animated primer on the basic of DNA, genes and heredity from Cold Spring Harbor Laboratory.
Dolan DNA Learning Center This is a really excellent page that has 28 different genetics tutorials that include animations, graphics, practice problems and links
23andme - this is one of a handful companies in a fast growing industry where companies analyze your DNA and send you information about your own personal genome. This is also the company that provided me with a complimentary analysis of my DNA in 2009. Although the results are fascinating, revealing and exciting, analyzing your own should be done with caution because you need to know how to interpret and utilize the information gained. In some circumstances, the situation may require that receive genetic counseling.
DNA Interactive - Discovering DNA Structure and Beyond from Cold Spring Harbor Laboratory.
Gel Electrophoresis - a step by step guide.
The O.J. Simpson Trial DNA Evidence - a list of the 45 blood stains introduced at trial along with their DNA evidence.
DNA Day - April 25th is National DNA Day
Crime Scene Investigator - Overview of best way to collects and preserve crime scene evidence.
DNA from the Beginning - (DNA, genes and heredity infomration from Cold Spring Harbor Laboratory)
Dolan DNA Learning Center (This is a really excellent page that has 28 different genetics tutorials that include animations, graphics, practice problems and links)
'GenPets' - What do you think about these?
Discovering the Genome (form the UPenn)
DNA Land & Molecularium (Rennselaer Polytechnic Institute)
Study Guides
POGIL DNA Structure & Replication (pdf)
POGIL Gene Expression - Transcription (pdf)
POGIL Gene Expression - Translation (pdf)
POGIL Genetic Mutations (pdf)
DNA Quiz from The Royal Institution (website)
Ch.4 Class Notes (pdf)
Chapter Objectives and Essential Vocabulary (Google Doc)
Chapter 4 Key Terms (pdf)
Forensic DNA Fingerprinting (pdf)
Molecules of Inheritance (website)
DNA Replication (Bozeman Science, 10:09 min.)
PowerPoint Presentations
Chapter 4 Background Information
DNA Structure & Function (pptx)
Sources of DNA (pptx)
RFLP & DNA Fingerprinting (pptx)
Recombinant DNA and Applications (pptx)
Sickle Cell & Gel Electrophoresis - how we use this technique to ID a person's genotype (pptx)
Activities
DNA Extraction Activity (pdf)
DNA Extraction - Why Use Detergent? (pdf)
Advanced Paper DNA Model (pdf)
Shorter, simplified directions for Paper DNA Model (pdf)
' Biotech Stocks are Hot' Stock Market Activity (pdf)
DNA Fingerprinting Scenarios (pdf)
Casting Agarose Gels Protocol - refer to p. 117 of the J. Kirk Brown textbook.
Laboratory Investigations
Lab 1: Restriction Site Prediction Using NEBcutter Protocol - refer to p. 75 of the J. Kirk Brown textbook.
Lab 2: Casting Agarose Gels Protocol - refer to p. 117 of the J. Kirk Brown textbook.
Lab 3: Dye Electrophoresis - refer to p. 119 of the J. Kirk Brown textbook.
Lab 4: Bio-Rad Restriction Digestion and Analysis of Lambda DNA - refer to p. 121 of the J. Kirk Brown textbook. For additional notes for this lab click this link: Lambda DNA Notes. For more detailed lab procedures click this link: Bio-Rad Restriction Digestion and Analysis of Lambda DNA.
Lab 5: Forensic DNA Fingerprinting - refer to p. 126 of the J. Kirk Brown textbook.
Lab 6: Plasmid Mapping - refer to p. 131 of the J. Kirk Brown textbook.
Virtual Laboratory Experiments
Gel Electrophoresis
Gel Electrophoresis Virtual Lab (University of Utah)
CSI Wildlife & DNA Profiling using STRs
Part 1: CSI Wildlife: Analyzing Genetic Evidence - Handout 1 (pdf)
Part 2: CSI Wildlife: Using Genetics to Hunt Elephant Poachers - Handout 2 (pdf)
Part 3: CSI Wildlife: Frequency Primer - Handout 3 (pdf)
Part 4: DNA Profiling using STRs (pdf)
Bioethics
Limited Medications. Who Gets It? (pdf, Daugherty textbook)
Videos & Animations
DNA Replication
DNA Replication (Bozeman Science, 10:09 min.)
DNA Replication animation (YouTube, 3:37 min.)
DNA Gel Electrophoresis 3D Animation (YouTube, 0:32 min.)
Transcription & Translation
Transcription animation This is an excellent animation of the process of TRANSCRIPTION.
Translation animation This is an excellent animation of the process of TRANSLATION.
DNA & RNA
HHMI Video Animations - DNA & RNA
The Art of DNA Folding. This animated video shows how and why DNA folds (YouTube, 8:27 Min.)
Central Dogma of Biology, 3D Animation (DNALC, 2:51 Min.)
How DNA is Packaged, 3D Animation (DNALC, 1:30 Min.)
Interesting Webpages
DNA through Nobel Prize.org Learn about genetics and DNA through this interactive site.
DNA to Protein From DNA to protein - a comprehensive site from The University of Utah.
DNA from the Beginning - an animated primer on the basic of DNA, genes and heredity from Cold Spring Harbor Laboratory.
Dolan DNA Learning Center This is a really excellent page that has 28 different genetics tutorials that include animations, graphics, practice problems and links
23andme - this is one of a handful companies in a fast growing industry where companies analyze your DNA and send you information about your own personal genome. This is also the company that provided me with a complimentary analysis of my DNA in 2009. Although the results are fascinating, revealing and exciting, analyzing your own should be done with caution because you need to know how to interpret and utilize the information gained. In some circumstances, the situation may require that receive genetic counseling.
DNA Interactive - Discovering DNA Structure and Beyond from Cold Spring Harbor Laboratory.
Gel Electrophoresis - a step by step guide.
The O.J. Simpson Trial DNA Evidence - a list of the 45 blood stains introduced at trial along with their DNA evidence.
DNA Day - April 25th is National DNA Day
Crime Scene Investigator - Overview of best way to collects and preserve crime scene evidence.
DNA from the Beginning - (DNA, genes and heredity infomration from Cold Spring Harbor Laboratory)
Dolan DNA Learning Center (This is a really excellent page that has 28 different genetics tutorials that include animations, graphics, practice problems and links)
'GenPets' - What do you think about these?
Discovering the Genome (form the UPenn)
DNA Land & Molecularium (Rennselaer Polytechnic Institute)
Study Guides
POGIL DNA Structure & Replication (pdf)
POGIL Gene Expression - Transcription (pdf)
POGIL Gene Expression - Translation (pdf)
POGIL Genetic Mutations (pdf)
DNA Quiz from The Royal Institution (website)
Instructional Videos
Agarose Gel Electrophoresis